Prognostic value of lymph node yield during nephroureterectomy for upper tract urothelial carcinoma

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A critical appraisal of the value of lymph node dissection at nephroureterectomy for upper tract urothelial carcinoma.

OBJECTIVES To perform a population-based analysis of the potential staging or prognostic value (or both) of lymph node dissection (LND) in patients without nodal metastases vs no LND. In several previous reports, LND in patients with upper tract urothelial carcinoma (UTUC) treated with nephroureterectomy (NU) was associated with better survival relative to no LND (pN(x)), even in the absence of...

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Laparoscopic nephroureterectomy for upper tract urothelial carcinoma – Update

Upper urinary tract urothelial carcinomas (UTUCs) are uncommon and account for only 5%-10% of urothelial carcinomas. Pyelocaliceal tumors are about twice as common as ureteral tumors. Sixty percent of UTUCs are invasive at diagnosis. Radical nephroureterectomy, including the excision of the distal ureter and bladder cuff is standard of care for treatment of localized UTUCs, because of the high ...

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Prognostic impact of preoperative statin use after radical nephroureterectomy for upper urinary tract urothelial carcinoma

PURPOSE The objective was to investigate the impact of statin use on prognosis after radical nephroureterectomy for upper urinary tract urothelial carcinoma (UTUC). MATERIALS AND METHODS A retrospective review of medical records identified 277 patients who underwent radical nephroureterectomy for primary UTUC at Asan Medical Center between January 2006 and December 2011. Information on preope...

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Prognostic significance of sarcopenia in upper tract urothelial carcinoma patients treated with radical nephroureterectomy

We investigated the prognostic significance of sarcopenia in upper tract urothelial carcinoma (UTUC) patients treated with radical nephroureterectomy (RNU). The skeletal muscle index (SMI) was calculated from computed tomography images. Sarcopenia was defined as SMI <43 cm(2) /m(2) for males with body mass index <25 kg/m(2) , <53 cm(2) /m(2) for males with BMI ≥25 kg/m(2) , and <41 cm(2) /m(2) ...

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Clinicopathological prognostic factors for upper tract urothelial carcinoma

INTRODUCTION The aim of the present study was to evaluate the influence of clinicopathological factors including age, gender, tumor grade, tumor stage, lymphovascular invasion (LVI), tumor necrosis and previous history of non-muscle invasive bladder cancer on outcomes of patients with upper tract urothelial carcinoma (UTUC) treated with radical nephroureterectomy (RNU). MATERIAL AND METHODS A...

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ژورنال

عنوان ژورنال: Urologic Oncology: Seminars and Original Investigations

سال: 2017

ISSN: 1078-1439

DOI: 10.1016/j.urolonc.2016.11.002